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The 1st Frontier Research Initiative Symposium
Tissue Remodeling in Cancer&s_comma; Inflammation and Chronic Diseases
June 8&s_comma; 2009. 13:00-18:20
Lecture room&s_comma; 2nd building&s_comma; Institute of Medical Science&s_comma; University
of Tokyo
(Poster session: June 8&s_comma; 2009. 15:00-16:15)

1:00 - 1:10 PM Opening Remark by Motoharu Seiki
1:10 - 1:45 PM Jeffrey W. Pollard (Dept. of Developmental and Mol.
Biology&s_comma; Albert Einstein College of Medicine&s_comma; USA)
“Macrophages and Metastasis”
1:45 - 2:20 PM Erik Thompson (Dept. Surgery&s_comma; St. Vincent’s Institute
and University of Melbourne&s_comma; Australia)
“Matrix metalloproteinase involvement in the PMC42 Human
Breast Cancer EMT System”
2:20 - 2:40 PM Beate Heissig (The Institute of Medical Sciences&s_comma;
University of Tokyo&s_comma; Japan)
“Plasminogen activators regulate myeloid-cell dependent
neoangiogenesis during tissue regeneration”
2:40 - 3:00 PM Tae-Hwa Chun (The Institute of Medical Sciences&s_comma;
University of Tokyo&s_comma; Japan)
“Collagenolytic Remodeling of the 3-D Microenvironment and
Insulin Signaling in Obesity Initiation”
3:00 - 4:15 PM Poster session

4:15 - 4:50 PM Christopher M. Overall (Centre for Blood Research&s_comma;
University of British Columbia&s_comma; Canada)
“Metadegradomics: Towards understanding the impact of the
protease web on the proteome in inflammation”
4:50 - 5:25 PM Yoshifumi Itoh (Dept. Matrix Biology&s_comma; Kennedy
Institute of Rheum. Imperial College London&s_comma; UK)
“Temporal and spatial regulation of MT1-MMP: an essential
mechanism for cellular invasion”
5:25 - 5:45 PM Naohiko Koshikawa (The Institute of Medical Sciences&s_comma;
University of Tokyo&s_comma; Japan)
“Pericellular proteolysis by MT1-MMP promotes invasive growth
of tumor cells”
5:45 - 6:20 PM Elizabeth Williams (Monash Institute of Medical
Research&s_comma; Monash University&s_comma; Australia)
“High content screening identifies compounds modulating
tumour cell plasticity”

FRI Management Office
TEL 03-5449-5254
FAX 03-5449-5496
E-mail: office@ims.u-tokyo.ac.jp
Beate Heissig&s_comma; Tae-Hwa Chun&s_comma; Naohiko Koshikawa Motoharu Seiki