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12.29 神経生化学セミナーのご案内/ Neurochemistry Seminar Annoucement

Title: CaMKII autophosphorylation&s_comma; a fast track to memory
Lecturer: Karl Peter Giese&s_comma; Ph.D. 
Affiliation: Professor of Neurobiology of Mental Health&s_comma; Centre for the
Cellular
Basis of Behaviour&s_comma; MRC Centre for Neurodegeneration&s_comma; Research Institute of
Psychiatry&s_comma; King’s College London

Time: December 29&s_comma; 2008 (Mon) 12:00~13:00
Place: Room 1303 (Seminar Room 5)&s_comma; 13th floor&s_comma; New Medical Research
Building
Host: Haruhiko Bito&s_comma; Department of Neurochemistry (03-5841-3560)
Supported by the Comprehensive Center of Education and Research for
Chemical
Biology of the Diseases&s_comma; a Global COE Program from MEXT

References:
Hojjati MR&s_comma; van Woerden GM&s_comma; Tyler WJ&s_comma; Giese KP&s_comma; Silva AJ&s_comma; Pozzo-Miller L&s_comma;Elgersma Y. Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses. Nat Neurosci. 2007
Sep;10(9):1125-7.
Mizuno K&s_comma; Ris L&s_comma; Shnchez-Capelo A&s_comma; Godaux E&s_comma; Giese KP. Ca2+/calmodulin kinase
kinase alpha is dispensable for brain development but is required for
distinct memories in male&s_comma; though not in female&s_comma; mice. Mol Cell Biol. 2006
Dec;26(23):9094-104.
Irvine EE&s_comma; von Hertzen LS&s_comma; Plattner F&s_comma; Giese KP. alphaCaMKII
autophosphorylation: a fast track to memory. Trends Neurosci. 2006
Aug;29(8):459-65.
Irvine EE&s_comma; Vernon J&s_comma; Giese KP. AlphaCaMKII autophosphorylation contributes
to
rapid learning but is not necessary for memory. Nat Neurosci. 2005
Apr;8(4):411-2.
Peters M&s_comma; Mizuno K&s_comma; Ris L&s_comma; Angelo M&s_comma; Godaux E&s_comma; Giese KP. Loss of
Ca2+/calmodulin
kinase kinase beta affects the formation of some&s_comma; but not all&s_comma; types of
hippocampus-dependent long-term memory. J Neurosci. 2003 Oct
29;23(30):9752-60.
Cho YH&s_comma; Giese KP&s_comma; Tanila H&s_comma; Silva AJ&s_comma; Eichenbaum H. Abnormal hippocampal
spatial
representations in alphaCaMKIIT286A and CREBalphaDelta-mice. Science. 1998
Feb
6;279(5352):867-9.
Giese KP&s_comma; Fedorov NB&s_comma; Filipkowski RK&s_comma; Silva AJ. Autophosphorylation at
Thr286 of
the alpha calcium-calmodulin kinase II in LTP and learning. Science. 1998
Feb
6;279(5352):870-3.

 Giese先生は、CaMKIIalpha-T286Aノックインマウスの解析ならびに、CaMKK経路の解析に関して先駆的なお仕事を数々されてきました。このたびの来日の折り、東大にてご講演いただく機会を得ましたので、どうか奮ってご参加下さい。

--
尾藤晴彦
東京大学大学院医学系研究科
脳神経医学専攻 神経生化学分野
〒113-0033 東京都文京区本郷7-3-1
e-mail: hbito@m.u-tokyo.ac.jp
Tel: 03-5841-3559 Fax: 03-3814-8154



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