独立行政法人日本学術振興会 先端研究拠点事業
先端ライフワークショップ 骨と軟骨の分子制御 2008年12月2日ー5日 のお知らせ
骨・軟骨の分子生物学研究の国際シンポジウムを開催いたします
URL:http://www.tmd.ac.jp/mri/abjs/
参加費無料 要参加申し込み 難治疾患研究所・分子薬理学あて
【申込先】 東京医科歯科大学 難治疾患研究所 分子薬理学
〒101-0062 東京都千代田区神田駿河台２-３-１０ Tel/Fax 03-5280-8067
浦田圭乃 あて E-mail: turata.mph@mri.tmd.ac.jp
(住所・氏名・所属を記載 ； Faxまたはメール)
“Forefront on Advanced Bone and Joint Science 2008 “
-------- Molecular Regulation of Bone and Cartilage Tissues --------
―Symposium and Workshop―
Advanced Bone and Joint Science (ABJS)
International Collaboration Symposium between
Core to Core Program of Japanese Society for Promotion of Science (JSPS) &
Canadian Arthritis Network (CAN)
Co-sponsored by;
Global Center of Excellence (Global COE) Program
“International Research Center for Molecular Science in Tooth and Bone Diseases”
Medical Top Track Program
Venue: Tokyo Medical and Dental University （会場 東京医科歯科大学、御茶ノ水）
(Core to Core program&s_comma; Supported by Japanese Society for Promotion of Science http://www.jsps.go.jp/j-bilat/core_to_core/index.html).
Tuesday&s_comma; December2&s_comma; 2008
Opening
10:00 President Address Takashi Ohyama&s_comma;
Tokyo Medical and Dental University
Director Address Mami Oyama
Director&s_comma; International Program Department&s_comma; Japan Society for the Promotion of Science
CAN Address Jane Aubin
Canadian Arthritis Network
Introduction
10:10 Masaki Noda&s_comma; Tokyo Medical and Dental University
Session Tu-1: Skeletal Cell Lineage
10:30 Jane Aubin&s_comma; University of Toronto
The osteoblast lineage
11:30 Derrick Rancourt&s_comma; University of Calgary
Loss of discordant cells during micro-mass differentiation of embryonic stem cells into the chondrocyte lineage.
12:30-13:00 Break
Session Tu-2: Transcription Factors and Epigenetics
13:00 Erwin Wagner&s_comma; Spanish National Cancer Research Centre
AP-1 (Fos/Jun) functions in Health and Disease
14:00 Shigeaki Kato&s_comma; University of Tokyo
Epigenetic regulators for nuclear receptors
15:00 Break
Session Tu-3: Cell Signaling in Biology
15:05 Sandra S. McAllister&s_comma; Whitehead Institute for Biomedical Research
How do tumors get what they need?
16:05 Noriyuki Tsumaki &s_comma; Osaka University
Roles of bone morphogenetic protein signals in cartilage formation
Special Lecture
17:05 Henry Kronenberg&s_comma; Harvard University
Growth plate closure in the absence of PTHrP receptors
Social Hour with Buffet
18:15 Mixing at Garden Palace Hotel&s_comma; Tokyo&s_comma; 3F Room Hei-an
Wednesday&s_comma; December 3&s_comma; 2008
Session W-1: Tumors and Skeletal Reconstruction
09:00 Nora M. Navone&s_comma; University of Texas
Bone metastases from prostate cancer: a significant medical problem
10:00 Masataka Majima&s_comma; Kitasato University
Neuronal system-dependent facilitation of angiogenesis during tumor growth and chronic proliferative inflammation
11:00 Break
11:05 Ung-il Chung&s_comma; University of Tokyo
Osteogenic and chondrogenic factors during endochondral bone formation
12:05-13:00 Break
Session W-2: Genetics in Bone Research
13:00 Erwin Wagner&s_comma; Spanish National Cancer Research Centre
New approaches to study AP-1 gene functions in bone development
14:00 Shiro Ikegawa&s_comma; RIKEN
Genomic analysis of bone and joint diseases: Integrated approach from human and mouse genetics toward the disease genes and molecular pathogenesis of the diseases
15:00 Break
Session W-3: Bone Cell Regulation
15:05 Veronica Ulici&s_comma; University of Western Ontario
Kinase pathways in cartilage development and osteoarthritis
15:35 Hiroshi Kawaguchi&s_comma; University of Tokyo
Transcriptional regulation of chondrocyte differentiation.
16:35-16:40 Break
16:40 David Lee&s_comma; University of Toronto
In vitro tissue-engineered cartilage from sheep bone marrow stromal cells on a porous calcium polyphosphate substrate
17:10 Koichi Matsuo&s_comma; Keio University
Regulation of osteoblasts by osteoclasts.
Thursday&s_comma; December 4&s_comma; 2008
Session Th-1:Growth and Differentiation Modulators and DNA
09:00 Sandra S. McAllister&s_comma; Whitehead Institute for Biomedical Research
Systemic instigation of indolent tumor outgrowth requires osteopontin
10:00 Shigeaki Kato&s_comma; University of Tokyo
Hormonal control of DNA demethylation for gene activation
11:00 Break
11:05 Masaharu Takigawa&s_comma; Okayama University
Role of CCN2/CTGF/Hcs24 in skeletal growth
12:05-13:00 Break
Session Th-2: Tissue Formation and Cells
13:00 Rita Arbetman Kandel&s_comma; University of Toronto
Towards Engineering a Biological Joint Replacement
14:00 Mototsugu Eiraku&s_comma; RIKEN
Self-organized formation of polarized cortical tissues from ESCs
14:30 Yoichi Ezura&s_comma; Tokyo Medical and Dental University
Methylation status of CpG-islands in the promoter regions of signature genes
15:00 Break
Session Th-3: Catabolic and Anabolic Regulation of Bone
15:05 Yukiko Kuroda&s_comma; RIKEN
Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis
16:05 Tomoki Nakashima&s_comma; Tokyo Medical and Dental University
Molecular mechanism in osteoclastogenesis
17:05 Naoshi Ogata&s_comma; University of Tokyo
Molecular mechanisms underlying osteoanabolic action of PTH.
Friday&s_comma; December 5&s_comma; 2008
Session F-1: Signaling Molecules in Skeleton
09:00 Henry Kronenberg&s_comma; Harvard University
Multiple roles of Gs alpha in osteoblasts
10:00 Hiromichi Kimura&s_comma; Takeda Pharmaceutical Company Ltd
Effects of small molecule inhibitors of Hh signaling pathway in tumorigenesis and in postnatal bone development
11:00 Break
11:05 Arthur Vinicius Sampaio
Function of the Retinoid Signaling Pathway in Osteogenesis
12:05-13:00 Break
Session F-2: Skeletal Diseases and Cytokines
13:00 Nora M. Navone&s_comma; University of Texas
Androgen Receptor–Negative Human Prostate Cancer Cells Induce Osteogenesis through FGF9-Mediated Mechanisms
14:00 Akihiro Yasoda&s_comma; Kyoto University
Translational research of CNP/GC-B system for skeletal dysplasias
15:00 Break
Session F-3: Skeletal Pathology and Repair
15:05 Caroline Hoemann&s_comma; École Polytechnique
A novel medical device for articular cartilage repair based on in situ scaffold-guided cartilage regeneration
16:05 Jane Aubin&s_comma; University of Toronto
ENU mutagenesis for new mouse models of human bone disease
17:05 Closing
Masaki Noda&s_comma; Tokyo Medical and Dental University
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