難治疾患研究所
先端ライフワークショップ 幹細胞の制御と骨
平成19年10月28日(日)～31日(水)
東京医科歯科大学1号館9階特別講堂
平成19年10月28日(日)～31日(水)
●申込先 東京医科歯科大学 難治疾患研究所 分子薬理学 101-0062 東千代田区神田駿河台２-３-１０ Tel/Fax 03-5280-8067
申し込み先： 浦田圭乃 E-mail: turata.mph.mri.tmd.ac.jp (住所・氏名・所属をお知らせ下さい)
参加費: 無料
Program
「Stem Cell Regulation and Bone Science」-Symposium and Workshop-
Advanced Bone and Joint Science (ABJS)
Venue: Tokyo Medical and Dental University
(Core to Core program&s_comma;Supported by Japanese Society for Promotion of
Science http://www.jsps.go.jp/j-bilat/core_to_core/index.html).
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Sunday&s_comma; October 28&s_comma; 2007
Joint Symposium with Canadian Arthritis Network
9:20 Introduction Masaki Noda&s_comma;Tokyo Medical and Dental University
Session S-1: Canadian and Japanese Arthritis Research
9:30 Johnathan M Riley&s_comma; Canadian Arthritis Network
CAN: a model for network research
9:50 Nobuyuki Miyasaka&s_comma; Tokyo Medical and Dental University
Treatment strategies of rheumatoid arthritis in Japan; Present and future
10:10 Jean Legare&s_comma; Consumer Advisory Council Emeritus Member
The Canadian Arthritis Network’s unique model of consumer involvement in
research
Session S-2: Mesenchymal Cells and Organogenesis
10:20 Jane Aubin&s_comma; University of Toronto
Leukemia inhibitory factor effects on mesenchymal cell fate choice
and osteogenesis
11:20 Makoto Asashima&s_comma; University of Tokyo
In vitro organogenesis and transplantation in vertebrate development
12:20-13:20 Break
Session S-3: Molecular Bases for Skeletogenesis and Stem Cell Niche
13:20 Michael Underhill&s_comma; University of British Columbia
Delineating the molecular mechanisms underlying chondrogenesis
14:20 Toshio Suda&s_comma; Keio University
Quiescent hematopoietic stem cells in the endosteal niche
15:20-15:30 Break
Session S-4: Humoral and Cellular Control of Bone Metabolism
15:30 Yoichi Nabeshima&s_comma;Kyoto University
alpha-Klotho: a regulator that integrates calcium homeostasis
16:30 Henry Kronenberg Harvard University
Periosteal origin of the first osteoblasts in the primary
spongiosa
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18:00 Social Hour with Buffet (Medico、16F&s_comma; Bldg. B)
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Monday&s_comma; October 29&s_comma; 2007
Session M-1: Stem Cell Control and Skeletogenesis
9:00 Marius Wernig&s_comma; Whitehead Institute for Biomedical Research
Epigenetics of stem cell differentiation
10:00 Ung-il Chung&s_comma; Univ of Tokyo
Development of high-performance implant devices
11:00 Levent Akyurek&s_comma; Goteborg University
Filamin B deficiency in mice results in skeletal malformations
and impaired microvascular development
12:00-13:00 Break
Session M-2: Molecular Signaling in Cell Differentiation
13:00 Hiroshi Takayanagi&s_comma;Tokyo Medical and Dental University
Molecular mechanism of osteoclast differentiation
14:00 James R. Woodgett&s_comma;Samuel Lunenfeld Research Institute
Genetic analysis of the roles of glycogen synthase kinase-3 in
stem cell fate determination and signaling
15:00 President Address Akio Suzuki
Tokyo Medical and Dental University
Director Address Hiromichi Matsuo
International Program Department
Japan Society for the Promotion of Science
15:15-15:30 Break
Session M-3: Nuclear Events and Bone Regulation
15:30 Shigeaki Kato&s_comma; University of Tokyo
Osteoprotective action of sex hormones mediates nuclear sex
hormone receptors in osteoclasts
16:30 Konrad Hochedlinger&s_comma; Center for Cancer Research
Nuclear reprogramming and pluripotency
17:30 Hiroshi Kawaguchi
Transcriptional regulation of cartilage degradation during
osteoarthritis
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Tuesday October 30&s_comma;2007
Session T-1: Regulatory Signaling in Bone Cells
9:00 Henry Kronenberg&s_comma; Harvard University
PTH receptor signals that regulate development of osteoblasts
10:00 Toshihisa Komori&s_comma; Nagasaki University
Regulation of skeletal development and maintenance by Runx2
11:00 Jane Aubin&s_comma; University of Toronto
Estrogen receptor-related receptors in skeletogenesis
12:00-13:00 Break
Session T-2: Mesenchymal Cell Differentiation and Signaling
13:00 Bill Stanford&s_comma; University of Toronto
Defining the Mesenchymal Stem Cell - clonality and function
14:00 Anita Woods&s_comma; University of Western Ontario
Rho signalling pathways in chondrocyte differentiation and function
15:00 Hiroshi Kawaguchi&s_comma; University of Tokyo
Bone regeneration by FGF signaling
16:00-16:10 Break
Session T-3: Central System and Skeletogenesis
Moderators: Michael Underhill&s_comma; Hiroshi Kawaguchi
16:10 Shu Takeda&s_comma; Tokyo Medical and Dental University
A new aspect of central control of bone remodeling
17:10 Kenichi Shinomiya&s_comma; Tokyo Medical and Dental University
Fundamental and clinical study of magnetic field potentials of the
cervical spinal cord for evaluation of spinal cord function
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Wednesday October 31&s_comma; 2007
Session W-1: Nuclear Control of Cell Fate
9:00 James R. Woodgett&s_comma; Samuel Lunenfeld Research Institute
Regulation of nuclear oncogene functions by phosphorylation
10:00 Shigeaki Kato&s_comma;University of Tokyo
A novel signaling pathway of fat-soluble ligands of transcriptional
factor-type receptors through target protein degradation
11:00 Konrad Hochedlinger&s_comma;Center for Cancer Research
Epigenetic reprogramming of adult cells by defined transcription factors
12:00-13:00 Break
Session W-2: Molecular Bases of Cell Regulation
13:00 Koichi Matsuo&s_comma; Keio University
Ephrin function in bone cell interaction
14:00 Levent Akyurek&s_comma; Goteborg University
Filamin A promotes VEGF-A activity through the HIF-1α-mediated hypoxic
response
15:00 Marius Wernig&s_comma; Whitehead Institute for Biomedical Research
Generation of pluripotent stem cells through direct reprogramming of
fibroblasts
16:00 Closing Remark
Masaki Noda&s_comma; Tokyo Medical and Dental University
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