第6回日本生化学会春季シンポジウムが下記の要領で開催される。最新情報とリンクは「バイオ関係者、皆のホームページ」学会研究会でアクセスできる。


第6回日本生化学会春季シンポジウム(6th CGGH Symposium 1999)

「蛋白分解酵素による生物活性の制御とその医学的応用」
“Biological Roles of Proteolysis in Health and Disease”
会 期:1999年5月19日(水)から21日(金)

会 場:ルネッサンス・リゾート・ナルト
    〒772-0053 徳島県鳴門市鳴門町土佐泊浦字大毛16-45
    TEL 088-687-2580   FAX 088-687-2211

オーガナイザー:松田佳子(徳島大学・工学部・生物工学科)
        木戸 博(徳島大学・分子酵素学研究センター)
        鈴木紘一(東京大学・分子細胞生物学研究所)
        田中啓二(東京都臨床総合医学研究所)

主 催:日本生化学会・CGGHフォーラム
共 催:(財)国際協力医学研究振興財団
協 賛:日本分子生物学会
    日本細胞生物学会
    文部省特定領域研究(A)蛋白分解のニューバイオロジー
連絡先:〒770-8506 徳島市南常三島町2-1
    徳島大学工学部生物工学科 松田佳子
    TEL(088)656-7523,FAX(088)655-3161
    E-mail:matsuda@bio.tokushima-u.ac.jp
    

May 19 &s_comma; 13:00から    Registration

18:20から22:00 Session1 Activation of Bioactive Peptide and Receptor
Chairperson:Yoshiko Matsuda
Gary Thomas(Oregon Health Science Univ.&s_comma; USA)
“Furin: A gateway for the activation of bacterial and viral pathogens”
Lloyde Fricker(Albert Einstein College Med.&s_comma; USA)
“Biochemistry and Cell Biology of peptide processing carboxypeptidases”
Daniel B. Constam(Harvard Medical School&s_comma; USA)
“BMP processing and the role of Furin protease activities during mouse embryogenesis”
Akihiko Tsuji(Tokushima Univ.&s_comma; Japan)
“Regulation of PACE4 expression under dynamic bHLH network and its physiological importance”
Tadashi Yoshimoto(Nagasaki Univ.&s_comma; Japan)
“Role of proline-specific peptidases on the metabolism of bioactive peptides”
Akiyoshi Fukamizu(Tsukuba Univ.&s_comma; Japan)
“Activation and inactivation of the renin-angiotensin system: From genes to Physiology”


20 May&s_comma; 1999(Thu)

8:30から 9:00 Plenary Lecture
Nobuhiko Katunuma(Tokushima Bunri Univ.&s_comma; Japan)

9:00から12:30 Session2 Regulation of Protease Activity and Its Novel Medical Applicatiom
Chairperson:Hiroshi Kido
Bradley Katz(Axys Pharmaceuticals&s_comma; USA)
“Recruiting Zn+2 to mediate potent&s_comma; specific inhibition of serine proteases”
Andreas Bergner(Proteros Biostructures&s_comma; Germany)
“Crystal structure of human bII-tryptase: An interesting target for the treatment of inflammatory
 disorders”
LB. Schwalz(Virginia Univ.&s_comma; USA)
“Tryptase: The major protease of human mast cell secretory granules”
Hiroshi Kido(Tokushima Univ.&s_comma; Japan)
“The molecular pathogenesis of Influenza Virus and Sendai Virus infection: Proteolytic activation of viral infectivity and protease inhibitors as defensive compounds”
Akira Matsumori(Kyoto Univ.&s_comma; Japan)
“Pathogenesis of myocardial injury: Roles of cytokines&s_comma; mast cells and chymase”
Mizuo Miyazaki(Osaka Med. College&s_comma; Japan)
“Pathophysiological roles of chymase in cardiovascular diseases”
14:30から16:30 Poster Session 70から100

18:30から22:00 Session3 Novel Protease Systems and Their Physiological Function
Chairperson:Koichi Suzuki
Guy Salvesen(Burnham Institute&s_comma; USA)
“Caspase activation triggers apoptotic cell death”
Vito Turk(J. Stefan Inst.&s_comma; E. Kardelj Univ.&s_comma; Slovenia)
“Cysteine proteinases and antigen processing”
Yoshinori Ohsumi(National Inst. Basic Biol.&s_comma; Japan)
“Molecular mechanism of autophagy: Recent progress in study on bulk protein degradation”
Atsuko Sehara(Tokyo Metropolitan Inst. Med. Sci.&s_comma; Japan)
“Roles of metrins&s_comma; members of metalloprotease-disintegrins/ADAMs&s_comma; in morphogenesis”
Hiroyuki Sorimachi(Tokyo Univ.&s_comma; Japan)
“Physiological functions of calpain homologues”
Akhteruzzaman Molla(Abbot Lab.&s_comma; USA)
“Roles of HIV protease as a target for the therapy of AIDS”



21 May&s_comma; 1999(Fri)

9:00から12:30 Session4 Recent Progress in Research on Ubiquitin/ Proteasome
Chairperson:Keiji Tanaka
Takashi Toda(Imperial Cancer Research Fund&s_comma; UK)
“The role of ubiquitin-dependent proteolysis in cell cycle regulation”
Keith Wilkinson(Emory Univ.&s_comma; USA)
“Deubiquitinating enzymes as regulators of ubiquitin-dependent process”
Yinon Ben-Neriah(Hebrew Univ.&s_comma; Israel)
“NF-k B activation: a paradigm for signal transduction through the ubiquitin-proteasome
 system”
Keiji Tanaka(Tokyo Metropolitan Inst. Med. Sci.&s_comma; Japan)
“Proteasomes and antigen processing”
Takehiko Koide(Inst. Himeji Tech.&s_comma; Japan)
“Proteasomes as a key enzyme in the quality control in the endoplasmic reticulum”
Kazuhiro Iwai(Kyoto Univ.&s_comma; Japan)
“Oxidation-induced ubiquitination of iron regulatory protein 2: Implications for degradation of oxidized proteins”