米国University of Michigan Mental Health Research Instituteが下記の要領でポスドクを募集中だ。

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ポストドクの募集

ミシガン大学の植田哲史教授からの依頼です。
研究内容は神経生化学の分野ですが、グルタミン酸のシナプティックベシクルへの取り込みを制御する因子の分子生物学的解析に従事する人を求めています。

詳しくは、直接問い合わせてください。日本語で結構ですが、E-mailの場合は英語にてお願いします。なお、植田教授は京都大学理学部出身で、在米30年以上になります。

We are concerned with the regulation of neurotransmitter release&s_comma; in particular glutamate and GABA release&s_comma; from synaptosomes via modulation of the amount of glutamate or GABA in synaptic vesicles within the synaptosome. The modulation of vesicular content of glutamate or GABA will be achieved by the inhibitory protein factor&s_comma; referred to as IPF&s_comma; which has the ability to reduce the
accumulation of glutamate into isolated synaptic vesicles. We have isolated this
protein and characterized (see Proc. Nat&s_quote;l Acad. Sci. USA 94:4137-4142&s_comma; April 15&s_comma; 1997). It is a potent inhibitor&s_comma; with an IC50 value of 25 nM under our assay conditions for vesicular glutamate uptake. Recently we have obtained evidence that IPF&s_comma; when incorporated into synaptosomes&s_comma; reduces exocytotic release of
glutamate from the synaptosome (unpublished observations).

We are looking for an individual who has recently received the PhD degree and who has expertise in molecular biology&s_comma; and preferably experience in protein purification&s_comma; as well as a keen interest in the molecular mechanism and
regulation of neurotransmitter release and/or the relationship between vesicular neurotransmitter content and various CNS diseases.

The annual salary is comparable to that of the NIH postdoctoral fellowship.However&s_comma; depending on the candidate&s_quote;s degree of expertise and qualification&s_comma; it could be negotiable.

Interested candidates should contact me at:

Email--tueda@umich.edu;
Fax--734-647-4130; Phone--734-763-3790; Mail--Tetsufumi Ueda&s_comma; Professor of
Pharmacology&s_comma; Mental Health Research Institute&s_comma; University of Michigan&s_comma; 205 Zina
Pitcher Place&s_comma; Ann Arbor&s_comma; MI 48103-0720&s_comma; USA.